In a similar vein to Fish48's post. If you always cull defective fish, there is no faster way to improve the blood line than inbreeding. Because inbred fish will show all of the defects that exist in their parents you can view it one of two ways. You can become distressed that a percentage will have recessive bad genes reinforced and that they become obvious in the fry or you can be encouraged that the bad genes will show up and you can cull them, thereby improving the genetic pool of your fish. The end result of inbreeding depends mostly on you, the breeder. If you are too soft hearted to cull defectives, don't allow inbreeding. If you are a pragmatic breeder with an aim to improve the fish, there is no faster way than inbreeding. It takes a very committed breeder to pass up the joy of new fish and feed his defectives to his carnivores, but that is what it takes to actually improve the breed. Otherwise, the best that you can expect is a diverse gene pool maintained by exogamy or similar techniques that mimics what might happen with no intervention in the wild.