What is your purpose of breeding? Are you trying to keep a strain going? If so, you want to make sure you know which female and which male are mating. They should be isolated pairs for mating. If you don't care and want all the fish to just produce babies, there's less care in the decision.
You still want three females to every male for the first male and two for every male after that. Unless it is for a small period of time, I would not put a female in with the males as they will constantly be harassing the female.