I'm just commenting on a couple of general questions you raised in this thread, as it may help you and others going forward.
Last night I found 2 green neon tetra with ich pretty bad. Why just them? No one else seems affected.
This is not surprising;
Paracheirodon simulans is an extremely sensitive and delicate species, much more than its two cousins even. Parameters may have something to do with this. Soft (less than 4 dGH) and acidic (pH 6.0 or below) water essential for long-term health, temperature 23-30C/73-86F. I know you are familiar with this, but it is the temperature that may be relevant here. Water temperature in P. simulans' natural habitats has been recorded to range between 24.6-35.2°C/76.3-95.3°F and it may have evolved a natural tolerance to high temperatures (Marshall et al., 2011). This species is sometimes found in the same waters as the cardinal tetra (termed sympatric) and both fish have identical water parameter requirements. In temperature however the cardinal tetra
P. axelrodi inhabits waters that do not exceed 30°C, whereas
P. simulans can be found in watercourses with a temperature that can surpass 35°C (Campos, et al, 2017).
I mention this in connection with a recent issue I have had. I moved last May, and after setting my (fewer) tanks up, in June I had the opportunity to acquire a group of 18 of this species to add to the three remaining ones from several years ago. I have always kept the temperature around 25C (76F) in their tank, which they share with pencilfish (
Nannostomus eques), Ember Tetra (
Hyphessobrycon amandae), and
Corydoras pygmaeus. In January I noticed what I assumed might be ich on several of this species, though it may have been something else entirely. They had been fine from June until January. I raised the temperature to 80F (26C) and did nothing else. I will not use any chemicals/medications with these fish, except for salt, and I thought I might get to that in stages. I lost half of them in a very short space of time (fairly quick dwindling numbers had actually been what alerted me to the problem), but once the heat was up whatever it was has cleared up with no additional losses. The tank has remained around 80F for the last two months, and I must say the P. simulans are brighter and seem to be enjoying the higher temperature.