Yes, lol, try to make your first suck count, as it may be the only one with air!
The difference between substrate cleaning with gravel and with sand is minor. With gravel you plunge the hard clear plastic cylinder down into the gravel and let the captured gravel be churned by the upwelling water. With sand, first of all its easier to use either a significantly smaller cylinder or to use simply a piece of clear flex hose and what you do is practice holding it somewhere a few inches above the sand and waving your fingers around a little to stir up the debris, then you suck up the debris up in the water with the hose. A good technique is to block the hose with your thumb and then open it when you want to suck up some debris. Some sand will always get lost but sand is cheap and some day down the road you can just add an extra scoop and all the lost sand will be made up! A good tip is that the more you plant your substrate the fewer areas you'll be able to get at and clean anyway! (of course you gotta learn how to keep those plants alive, lol)
~~waterdrop~~