Hi there
As neat R/O or distilled water contains no minerals it can be detrimental to the health of the fish (probably more due to the fact that there is nothing present to buffer the pH of the water) and it is the resulting wide swings in pH that could endanger the life of your fish.
For my south american dwarf tanks, I run my R/O water to a 350 litre water butt, I then circulate this water through a 150 litre water butt filled with irish moss peat for at least 24 hours before I use it for water changes. This gives me 1 degree GH, <1 degree KH and a pH of about 5.6. Seems to do the trick with most of the wild caught south american dwarves spawning, now if only the Nanochromis transvestitus would follow suit as well.....
There are commercial preparations fr remineralising the water to the appropriate hardness, and people will mix with tap water as well to adjust to the required hardness.
Andrew