Well, I haven't dosed Prime today, I'm testing again tomorrow prior to feeding, and then cleaning on Wednesday and possibly testing again. For the levels I've seen on the Nutrafin test (if it can be trusted), I'm not going to be cleaning every day or every other day, it'll be far too stressful on the Clown Loach who is stressed enough as it is, and I worry that much already that testing and looking things up on the internet takes up a lot of my free time when I'm not at work. Adding even more cleans in every week and my OCD is never going to get any better, it's already exhausting me and I'm avoiding doing certain things with my free time in case I'm neglecting the fish (I do the guilt tripping a lot). I'm going over-board with the testing, but if I don't do it almost every day now, I'm 'neglecting' the fish - I need to check and double-check, to compare and to make absolutely certain. One reason I really hope someone can step forward and help with the rehoming, it just cannot go on like this...
I never did this many tests earlier in the year, I was doing 9-10L changes twice a week, and never noticed any adverse effects (without dosing Prime except in the new water which I left to stand for 24 hours as I always have done). I did however clean the filter once a week and only removed the middle polyester pad every other week (rotating it so both ends were used for a week); the foam pads are the long-term pads and last for years at a stretch before anyone worries that I've been replacing the wrong filter media.
As for the API kits and measuring total nitrites and nitrates - probably far more useful at higher levels. I know the nitrates one is, but it's almost impossible to read and very fiddly to get right.
I've also ordered a new impeller (I've used the current one for 5 1/2 years almost - now realised not a good idea), maybe the old one might be causing issues. Also, how often should the air inducer on a Fluval filter - or any filter - be changed? I'm loath to touch that because from some images online, I'm thinking I'll end up breaking the top of the filter and any issues with the impeller will be the least of my concerns.