That depends on what you stock it with and how heavily you stock it.
I keep big messy predators and the tank is currently overstocked so i probably spend 4 hours a week doing water changes and vacuming the substrate, with less or smaller fish i could cut this down to around 2 hours. Every couple of months or so i spend an extra couple of hours stripping down the filters and giving all the media a rinse.
The key thing is getting the right equipment to do the job, a long hose or python to take and return water to the tank is a must and having several large buckets for washing media helps no end