The beam should always be laid on edge because that is the direction that can take the most weight. If you take an extreme example, think of a very thin board like a wooden rule. It is easy to bend and break that rule with your hands if you bend it the 1/8 inch direction but you will not be able to easily break it with your hands in the other direction. You want the strength up and down to hold up the floor so set the 4 x 8 so that the 8 inches, 7.25 really, is vertical and the 4 inches, 3.5 really, is in the horizontal direction. By setting it on edge like that, you have made it like the wide direction that you were finding hard to break in our example.
A tank that has been set up for a while may or may not be warped. Have a close look where the corners come together and see if all of the glass is aligned the way you would expect. If one piece of the glass is not aligned straight with the one next to it, walk away and leave the tank where it is. (I am talking about a corner where an end and the front or the back come together. At the top, the front and the end should be the same height. If not, something has shifted and you only want the tank if you are willing to rebuild it.)