Well dave if we're talking less than 1ppm of phosphates, then yes, over time that refugium will help. It will also help you keep your nitrates low as time goes on. For example, I have about a 15 gallon refugium compartment in my sump under my 45g tank (the whole sump is about 28gallons). Its about oh, 1/3rd full of chaeoto and my phsphate problems are extremely minimal. Moreover, my nitrates have been zero since about the 1st month of the tank's life. For a tank of your size, a 20-30 gallon refugium full of chaeot would be very beneficial to the longterm phosphate and nitrate removal of the tank. Just my $0.02