Yes and no... There was a time when I added few drops when changing water. Nowadays I put some because especially on summer (when people are away from city) tap-water is not so good. It's very good, you drink it etc, but not good for sensitive fishes. I have sensitives fishes so that I try to minimize stress. But no way, Im not going to add so much coonditioners like it said in bottle. Those chemicals aren't very good for fishes either if you add them too much.
Amines are quickly oxidized nitrites and nitrates, so when doing water changes, amines will "disappear" quickly and if you're doing small water changes, Im not sure, do you actually need to add anything to water - if you water is enough pure -> you can drink it yourself too... Of course in places where tap-water is terrible, you need to add water conditioners.