Depends what you call 'regular filters' (I'm guessing internal by the way you described the external), you should be ok if the stated size of any filter (or combined) is roughly double the volume of you tank (like to overfilter, especially if you have alot of fish or messy fish, you can cut back if your tank will be understocked). The one the LFS tried to sell you would probably be an external canister, these should also do fine.
Generally for bigger tanks people recommend external filters as they are usually more powerful and can handle a greater bioload than internals. Though there are some pretty beefy internals out there.
So what I would say is depending on your stocking levels and type of fish you are going to put into the 100 gallon, it might be best to opt for an external filter as these tend to be suited better for bigger tanks (though like I said if you like internals that can provide adequate filtration they should also do the job).