Yes i'm afraid so, how many gallons or litres is the tank, how many fish and which type, can you post water stats in ammonia,nitrite,nitrate,and ph, its bacterial, what your location for a med, plus can you issolate the fish.
Also is the fish having trouble opening and shutting the mouth.
Also check the fish for red patches on the belly.
Any red patches on the tummy area.
You do realise that the red tailed shark needs a 40gal tank, and he will be aggressive and that tank is way to small for him, i will have to check the zebra fish out and the candy loach.
I would add a bacterial med to the tank, are you sure he hasn't damaged his mouth on something in the tank.
Is the zebra fish a danio or one of them fish that glow in the dark.
The candy loach needs a bigger tank as well.