Actually, it can be run on a temporary basis without anything permanent. I ran mine off a powerhead and when I finished clearing up a green water problem on one tank, I simply moved it to another tank. It's actually still connected to the powerhead and I could start it running again at a moment's notice. It is true though that it has to run off a power head, inline with an external filter or some other method of orcing/pulling water through it.Cons:
[*]requires out of tank plumming to be installed if not already used (not sure about this as there may be a hang on unit but any model I've ever seen is used in combo with a sump/wet dry filter cumbo)
Although it wont ever be able to kill 100% of the nasties in a tank, it will come close. The longer it is allowed to run the closer it wll come to getting them all. I guess it's kind of like taking 100 pieces of something and every day you remove half of what's left. Soon you will be working in fractions of a piece and a year later, there will still be some left but it will only be a very small fraction of a single piece.[*]only treats water that flows through it, ie. does not treat whole tank and therefore in the tank things like algae and disease can still survive