Eyes are sunken in
Wow. Sunken eyes are usually associated with Aeromonas / Pseudomonas bacterial infections which have gone systemic (gained entry to the blood stream) and sometimes you may see fish which have been parasitized by Flukes, for example, to such an extent that they have essentially bled to death through the gills and skin. The loss of protein and plasma in the fish leaves them wasted and emaciated and the eyes will sink in. Once it gets this far, the prognosis is extremely poor. I've never seen a fish with sunken eyes to survive. Never. If the fishes' head is shaped like an arrow head, and it's shimmying in the water, and the fins are clamped, the fish is a goner. This is disturbing, of course, but don't let it stop you from saving the fish that have not gotten this far! You owe it to yourself, and to the remaining fish to aggressively treat. Here's what you do: Salt the main system according to these instructions. Inject any fish which are valuable. Try as much as possible to make a diagnosis of a parasitism if possible using a microscope. If this is not a possibility, shotgun remedies (there are two) could be considered.
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