I have a rio 180, with mbuna in it. There are 6 yellow tail acei, 6 rusties and 6 ps. saulosi in there atm, all between 2-4". I am planning on adding 6 of another species, but not sure which yet.
I would advise keeping larger groups of fewer species, it makes for a more peaceful tank and makes your life easier than if you have pairs of more aggressive fish.