I concur with what eaglesaquarium has posted, both times. Without live plants, keep the substrate clean by vacuuming into it with every water change. And I would increase the water change volume up to no less than 1/3 and preferably 1/2 the tank volume, every week. I'll add a bit of explanation if I may, so you will perhaps better understand why we are advising what we are.
You want to remove much of the organics (fish excrement and other biological matter like uneaten fish food, dead plant matter if you had live plants, etc) from the substrate in non-plant tanks because the breakdown by bacteria of this organic matter can cause nitrates to rise, pH to lower as the water acidifies, increase CO2, and add dissolved organics to the water. The GH and especially KH of the source water will work to buffer the pH aspect, but not the breakdown and nitrates. And nitrates should be as low as possible, certainly below 20 ppm and preferably no more than 10 ppm. In planted tanks this is usually easy to achieve, but in non-planted tanks it is the water change and removal of the substrate organics that keeps nitrates under control.
It is very true what another member said about bacteria in the substrate. In addition to the nitrifying bacteria that most think of, there is a host of other bacteria performing many functions that keep an aquarium healthy. However, all bacteria are very sticky and they live attached to surfaces...every surface covered by water in an aquarium will be a biofilm on which live millions of various bacteria. It is not easy to remove these, and certainly water changes and substrate vacuuming will not do this, so there is no real "downside" to these. Of course, this assumes other things are equal, such as fish load to the volume, compatible fish, water parameters reasonably similar between source and tank, and so forth.
Byron.