Ok, can you help us out with a bit more info on your tank and your fish?
A disease is eating your catfish? What kind of fish are they? What are the symptoms? Are the fins disintegrating or perhaps holes appearing on the fishes body?
Tank test readings would be a help also, can you tell us the PH, ammonia and nitrite. How often do you change some water in the tank?
Im sorry to have lots of questions and very little in the way of answers but without the info, my guess is as good as yours!!
Hope to hear from you soon,
Ken