Guppies in distress

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If there is carbon already in the filter it needs to be removed before any medication is added to a tank as carbon will remove the medication. If you can remove the carbon already there, put new in its place and throw the old away. Then when you add any other medication, remove this new carbon and throw it away.
 
Another worm symptom?
 

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If there is carbon already in the filter it needs to be removed before any medication is added to a tank as carbon will remove the medication. If you can remove the carbon already there, put new in its place and throw the old away. Then when you add any other medication, remove this new carbon and throw it away.
Yes, I removed the filter before treatment. I have put a fresh one in, after the 75%water change. Thank you! In that case, the medication is being removed now.
 

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